Aeris HPLC or UHPLC Column


Core-shell particle technology provides striking increases in peak capacity and resolution at lower backpressure, giving chromatographers the ability to achieve ultra-high performance on ANY brand and make of HPLC or UHPLC system.

AERIS NEW! Core-Shell Technology for Protein and Peptide Separations.

 A uniform porous silica layer is grown around a solid, spherical silica core, providing effective retention and selectivity with improved resolution, speed, and recovery. Next, optimizing the pore size and shell thickness for intact proteins or smaller peptide fragments provides well-defined depth penetration of biomolecules leading to maximum separation power.

TEM and SEM of Aeris™ PEPTIDE 3.6 µm Core-Shell Particles

The precise architecture of core-shell particles provides dramatic leaps in performance in two important ways:

  • The thin, porous layer, or "shell", decreases the diffusion path length, thus reducing the time it takes for biomolecules to adsorb/desorb into and out of the particles.
  • PUniform sizing and shape of the particles along with tight packing specifications reduces losses in efficiency and performance due to band broadening.


 Aeris core-shell technology

The result of the Aeris™ core-shell technology is:

  • 3.6 μm core-shell particles that can perform like sub-2 μm columns on both HPLC and UHPLC systems at a fraction of the pressure.
  • 1.7 μm core-shell particles that can provide higher peak capacities compared to fully porous sub-2 μm columns on UHPLC systems.

For more information, we welcome you to download the Phenomenex Aeris Product Guide at Phenomenex

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