Why should Polymer Characterization be important?
Are you interested to measure and determine the extent of the differences in the physical properties of a batch of polymer you receive from the previous batch?
Take two samples of polymer. They may both have the same chemistry (for instance, they may both be polyethylene), and yet may differ with one another in physical characteristics, such as in tensile strength, toughness, brittleness, melt viscosity, etc. These differences in physical characteristics are due to the difference in the distribution of molecular chain lengths. Each polymer sample will contain a distribution of molecules of different lengths, and it is the variation in the molecular weight distribution that account for their differences in physical characteristics.
This makes it important to measure the molecular weight distribution of polymers. Gel Permeation Chromatography/Size Exclusion Chromatography (GPC/SEC) is a reliable technique to characterize the molecular weight distribution of polymers. It is therefore a powerful and convenient analytical technique to help understand polymer performance.
An essential part of the characterization of any protein is the determination of its molecular weight. Proteins can be separated according to their size and molecular weight, using Size Exclusion Chromatography (SEC). SEC with Multi-angle light scattering detector has increasingly become the technique that is used for the quantification of protein aggregation, the determination of protein conjugate stoichiometry and the confirmation of the oligomeric state of a protein.
Different Approaches in Analytical GPC/SEC
While recognizing that GPC/SEC is most effective method to measure molecular weight distribution of polymers, there is nonetheless a need to realize that there are a number of different approaches in GPC/SEC to do so, and these differences lie mainly in the detectors and calibration options:
Complete turn-key solution
We offer complete turn-key systems for GPC/SEC with all detection methods:
from single instrument up to Client/Server solutions,
from one detector and conventional calibration up to multi-detection systems with advanced analysis methods.